Factors associated with inflammatory cytokine patterns in community-acquired pneumonia

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Factors associated with inflammatory cytokine patterns in community-acquired pneumonia.

Raised systemic levels of interleukin (IL)-6 and IL-10 cytokines have been associated with poorer outcome in community-acquired pneumonia. The aim of our study was to identify potential associated factors with increased levels of IL-6, IL-10, or both cytokines. We performed a prospective study of 685 patients admitted to hospital with community-acquired pneumonia. IL-6 and IL-10 were measured i...

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Patterns of cytokine expression in community-acquired pneumonia.

BACKGROUND Pneumonia continues to be a major cause of disease and death among patients worldwide. Aspects of the host response to infection, such as the release of cytokines, may be contributing to the persistent morbidity and mortality. METHODS Plasma levels of cytokines interleukin (IL)-1 beta, IL-6, and tumor necrosis factor alpha (TNF-alpha) were measured in critically ill patients with p...

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Bacterial Pathogens Associated with Community acquired Pneumonia.

2. The use of oropharyngeal aspirate as the sample for isolation of bacterial pathogens associated with community acquired pneumonia (CAP) raises many questions. This is again highlighted by the isolation of organism like Acinetobacter and Citrobacter species from CAP cases. The value of isolating bacterial organisms that are frequently detected in the upper airways of children (eg, Streptococc...

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Phagocyte function and cytokine production in community acquired pneumonia.

BACKGROUND It is possible that many deaths from pneumonia may involve the generation of inflammatory mediators and tissue damage by activated phagocytes. To test this hypothesis phagocyte function, plasma levels of interleukin 6 (IL-6), tumour necrosis factor alpha (TNF alpha), and soluble interleukin 2 receptor (IL-2R), disease severity, and outcome have been examined in 46 patients with commu...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2010

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.00040710